The five remaining GOP presidential candidates gathered for the 10th GOP debate at the University of Houston in Texas on Thursday night.

During the first opening minutes, Florida Senator Marco Rubio attacked Donald Trump’s liberal stance as well as his business record.

“In fact, very recently, he was still defending Planned Parenthood. He says he’s not going to take sides in the Palestinians versus Israel. These are concerning things,” Rubio commented. “And so, yes, I have a doubt about whether Donald Trump, if he becomes president, will replace Justice Scalia with someone just like Justice Scalia.”

Rubio also attacked Trump’s business record, asserting Trump’s hiring of foreign workers before American workers.

"You're the only person on this stage that's ever been fined for hiring people that worked on your projects illegally," Rubio said.

Texas Senator Ted Cruz mentioned the lawsuit against the university bearing Trump’s name for defrauding students.

Thursday night’s debate was the first time the Republicans initiated an attack on Trump, the billionaire businessman who has been leading the race.

John Kasich and Ben Carson, on the other hand, avoided making criticisms of Trump, staying on the sidelines of the debate.