Amanda Seyfried has worked with Seth MacFarlane in "A Million Ways to Die in the West" and now the two have teamed up again for "Ted 2," where the adventures (and misadventures!) of the moving and talking teddy bear will continue.

The actress spoke with Screen Rant about the upcoming comedy, and how her character Samantha is different from her character Louise in "A Million Ways to Die in the West."

"Samantha is strong, laid back, and she's a happy girl. She's a hard working lawyer, but she's cool. She's somebody I'd want to know," said Seyfried, whereas Louise was incredibly mean.

Seyfried had such a fun time filming with MacFarlane and Mark Wahlberg, but their chemistry is just so amazing that the actress always felt like the third wheel among them.

"The collaboration is always great with Seth, I look forward to coming into work every day and seeing him. Mark is also so awesome, he's so easy and funny and such a pro!" she said.

One of the things she struggled with in making the film was the need to do improv. Seyfried admits that she's not so good with it, but the same cannot be said for MacFarlane and Wahlberg.

"A lot of the improve came from Mark and Seth because they are so smart and would just come up with so many funny things- their dynamic just allows for so much to happen. I don't necessarily join them, but I just watch and laugh hysterically," she said.

One thing Seyfried learned about doing comedy is that it's very important to be "grounded as much in reality as possible." When she was playing Karen Smith in "Mean Girls," Seyfried had to believe everything that she said even though it was "dumb dumb" because it's how they can keep the comedy moving along.

"She believes everything that she's saying, and if you can believe what you're saying it comes across as real," she said.

Prior to "Ted 2," Seyfried also starred in musicals such as "Mama Mia" and "Les Miserables," and given the opportunity, she would love to star in another one - "Wicked."

"I'd love to do more!" she said. "Every single interview I've been doing I'm trying to get the word out and put it out there, I've been training really hard for the role of Glinda the Good Witch in the adaptation of 'Wicked.' I'm dead serious about it, I'm doing to audition my pants off for it," she said.