Famed mathematician John Nash, whose life and genius inspired the Oscar-winning film "A Beautiful Mind" starring Russell Crowe has just lost his life due to a car crash in New Jersey on Saturday. He was 82.

According to Variety, Nash was with his 82-year-old wife Alicia Nash when the taxi they were riding crashed into a guard rail. Reports have it that the couple were not wearing seat belts and was ejected from the car when they crashed. A spokesman from the New Jersey state police was unavailable for comments.

Those involved in the making of the film "A Beautiful Mind" cannot help but feel for the tragic loss and extend their sympathies to the Nash family. Movie director Ron Howard tweeted, "RIP Brilliant #NobelPrize winning John Nash & and his remarkable wife Alicia. It was an honor telling part of their story  #ABeautifulMind."

Crowe also took to Twitter to offer his condolences: "Stunned...my heart goes out to John & Alicia & family. An amazing partnership. Beautiful minds, beautiful hearts."

Nash is a Nobel Laureate in Economics, and his academic achievements and struggles with schizophrenia were all documented in Sylvia Nasar's 1998 biography called "A Beautiful Mind," which later inspired the film with Crowe starring as John Nash and Jennifer Connelly as Alicia Nash.

The film was a success, grossing over $313 million worldwide. It won four Academy Awards, including one for Best Picture, Best Director, Best Adapted Screenplay, and Best Supporting Actress. Meanwhile, it was also nominated for Best Actor, Best Film Editing, Best Makeup, and Best Original Score.

Nash's mental health struggles almost affected his work in game theory, differential geometry, and mathematical research, which are now being used to develop economics, artificial intelligence, computer technology, and several other fields. He shared the 1994 Nobel Prize for his work in economics along with Reinhard Selten and John Harsanyi.

His wife was pregnant when Nash began showing symptoms of mental illness. Because of this, he resigned from his job and checked in to the McLean Hospital to get his schizophrenia treated. While he was there, their son John Charles Martin Nash was born. In fact, the boy was not named for over a year because his wife felt that John had a say in choosing their son's name.

A few years after though, John and Alicia divorced due to the stress brought about by his illness. After his discharge, John still lived in his wife's house but only as a boarder, and after showing significant improvement, John went back to work and he and his wife remarried in 2001.