Drew Barrymore is reaching out to her fellow females, empowering working mothers and telling them to stop feeling guilty.

The ‘Miss You Already’ star believes that busy moms are spending too much time feeling ashamed and regretting their circumstances for not being capable to do it all.

“I think we’re all hard on ourselves because we’re just trying our best,” she said in an interview with NY Daily News. “I don’t understand how women love to get on the guilt trip. It’s like we have guilt for breakfast, guilt for lunch, guilt for dinner and then we go to bed feeling guilty.”

On the other hand, fathers steer clear from such way of thinking.

“I used to think that I totally understood men,” the actress added. “Now I realize I do not understand anything about men. I’m so curious to know how they deal with it and from what I can tell, they don’t torture themselves the way we do.”

The Golden Globe-winning star will be handling more than a few struggles in her latest movie, 'Miss You Already,' which is set to hit theaters on Nov. 6.

Barrymore will co-star alongside Toni Collette, both of whom will be taking on the role of best gal pals whose friendship will be tested when Jess (Barrymore) gets pregnant and Milly (Collette) is diagnosed with cancer.

Australian actress Collette admitted that she and Barrymore did not know each other well before they began filming, but seemingly appeared close at the New York premiere of the movie this week.

“We’d met a couple of times,” Collette explained, “through mutual friends but we hadn’t really connected. I guess it wasn’t the right time but we got our time now!”

The actress is also pleased with how ‘Miss You Already’ depicts friendship between women, describing the story to be “refreshingly honest” as well as a “real authentic portrayal” of what it’s like to have a lifelong friend.

As for Barrymore, a former child star who went on to become a successful adult actress following her battle with drug and alcohol abuse in her younger days, she unveiled the memoir titled ‘Wildflower’ on Tuesday.

In this collection of life stories and events, she has written much about her profound friendships with female friends, such as fellow actress Cameron Diaz as well as producer and co-owner of Flower Films, Nancy Juvonen, who is presently married to Jimmy Fallon.

Barrymore also touched on the subject of her parents, stating that she never lived with her father, John Drew Barrymore, who also worked in the film industry; she has also never ate a meal with both of her parents. Her father passed away due to cancer in 2004.

The actress’ mother, Jaid, requested for her institutionalization during her younger teenage years. At the age of 15, Barrymore says she became a liberated adult, but is carrying on to provide financial support for her mother.

“Women drink wine together and talk about everything together and you grow up together...,” Barrymore stated as she defined a female friendship. “It’s one of the most important relationships you’ll ever get to have through the journey of life.”